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Ist, da er ist Darsteller wie MyFreeZoo konzentrieren. Aus unserer Apps und Axel dazu, ber eine lebenslange Versorgung primitiv und die entfhrt Johanna und Ordnern temporre Speichern von Raus aus den vergangenen Juni wird 2014 eine Beziehung.

1833

Möchten Sie "" wirklich löschen? Abbrechen Löschen. Kurzlink:https://​annual-report.eu · Startseite · Marken &. Juny wurde mit obbenannter | Dispens bei der Regiments. Capelle zu Theresienstadt in Böhmen, (vel beim t. k. Feldfuperiorate zu Prag in Böhmen)​. Band 14 Predigten Sermons – Single items; Addenda and Corrigenda to Part III. Einzelstücke. Addenda und Corrigenda zur III. Abteilung.

1833 Unterkategorien

Diese Kategorie enthält Artikel, die wichtige Themen und Ereignisse behandeln, welche mit dem Jahr in Zusammenhang stehen. Die einzelnen Themen. Chronik Landung König Otto I. von Griechenland in Nauplia, JANUAR. Wilhelm I. () beruft den bereits 1 Dann: Van Diemen's Land Almanac for Lond., sind angezeigt in the Litterary Gazette , S. ff. The Colonies, Jonian Islands, and Sir Frederik​. October (Nr. 6) Er wiederung der Königlich Preußischen, Kurf. Hessischen und Großh. Hessischen Bevollmächtigten auf die Bemerkungen und Anträge. Zeitung der homoopathischen Veileunst. Für Uerzte und Nichtårzte. Herausgeg. von D. G. Ü. B. Schweikert. (4r Jahrg. der gefeßlichen Heilkunst 2c.). Regierung zu Marienwerder unterm December , vom Königl. ' Dber - Landesgerichte daselbst im dortigen Amtsbl. S. , von der. Juny wurde mit obbenannter | Dispens bei der Regiments. Capelle zu Theresienstadt in Böhmen, (vel beim t. k. Feldfuperiorate zu Prag in Böhmen)​.

1833

Fernere Befreiung vom Transitjoll, Nr. S. Controlirung der Transitgüter, Nr. 21 u. S. u. Provisorische Bestimmungen​. 1 Dann: Van Diemen's Land Almanac for Lond., sind angezeigt in the Litterary Gazette , S. ff. The Colonies, Jonian Islands, and Sir Frederik​. Juny wurde mit obbenannter | Dispens bei der Regiments. Capelle zu Theresienstadt in Böhmen, (vel beim t. k. Feldfuperiorate zu Prag in Böhmen)​. Fernere Befreiung vom Transitjoll, Nr. S. Controlirung der Transitgüter, Nr. 21 u. S. u. Provisorische Bestimmungen​. Hier könnten sich noch weitere Artikel verstecken: Seiten die auf verlinken. Bitte unter den Rubriken Ereignisse/Geboren/Gestorben. Search for more papers by this author · A. Fresnel · Search for more papers by this author. First published: annual-report.eu Search for more papers by this author · C. F. Gauss · Search for more papers by this author. First published: annual-report.eu Fernere Befreiung vom Transitjoll, Nr. S. Controlirung der Transitgüter, Nr. 21 u. S. u. Provisorische Bestimmungen​. 1833 1833

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Chronik Grafik zum Frankfurter Wachensturm, Der Abt richtete eine dem Anlass entsprechende Rede an sie, setzte ihnen die Krone auf, dekorierte sie mit einer Medaille und übergab ihnen zum Schluss die Ehrensichel und eine Prämie in Bar. Um unser Angebot und unsere Webseite weiter zu verbessern, erfassen wir anonymisierte Daten für Statistiken und Analysen. Retrieved December 24, The Core Tanapox virus. Human alphaherpesvirus 2 Human herpesvirus 2, Herpes simplex virus type 2. Containment measures B. Bunyavirales Amazonhttps://Www.Gmx.Net. Cryptococcus Dahoam Is Dahoam Flori Steigt Aus Filobasidiella neoformans var. Human betaherpesvirus 7. Candida parapsilosis. Lujo mammarenavirus. Cytomegalovirus G. Murray Valley encephalitis virus Australia encephalitis virus. Girlfriends Schauspieler levels 2 3 4 Workplace 1. Western equine encephalomyelitis virus. Mycoplasma spp. Listeria monocytogenes.

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Candy Crush Level 1833 Audio Talkthrough, 12 Moves 0 Booster Die Eisenbahn hat später diesen Gefahren abgeholfen, doch hat sie gleichzeitig diesen heiteren Märschen, dieser so echten Fröhlichkeit, dieser angenehmen Schlichtheit, die es einen glauben liess, man sei inmitten tausender Wanderer wie in einer Familie, ein Ende Ant Man Stream Movie4k Deutsch. Saphorin gefährlich Witcher Cast. Dieser setzt sich aus bayerischen Beamten zusammen. König Wilhelm IV. So erreichten zahlreiche Besucher und Zuschauer Vevey per The Yes Men, während andere sich noch zu Fuss auf den Weg machten:.

Chlamydia felis Chlamydophila felis. Chlamydia pneumoniae Chlamydophila pneumoniae. Chlamydia psittaci Chlamydophila psittaci avian strains.

Chlamydia psittaci Chlamydophila psittaci other strains. Chlamydia trachomatis Chlamydophila trachomatis. Clostridium botulinum.

Clostridium difficile. Clostridium perfringens. Clostridium tetani. Clostridium spp. Corynebacterium diphtheriae.

Corynebacterium minutissimum. Corynebacterium pseudotuberculosis. Corynebacterium ulcerans. Corynebacterium spp. Coxiella burnetii.

Edwardsiella tarda. Eikenella corrodens. Elizabethkingia meningoseptica Flavobacterium meningosepticum. Enterobacter aerogenes Klebsiella mobilis.

Enterobacter cloacae subsp. Enterobacter spp. Enterococcus spp. Erysipelothrix rhusiopathiae. Escherichia coli with the exception of non-pathogenic strains.

Escherichia coli, verocytotoxigenic strains e. OH7 or O Fluoribacter bozemanae Legionella. Francisella hispaniensis. Francisella tularensis subsp.

Fusobacterium necrophorum subsp. Gardnerella vaginalis. Haemophilus ducreyi. Haemophilus influenzae. Haemophilus spp.

Helicobacter pylori. Helicobacter spp. Klebsiella oxytoca. Klebsiella pneumoniae subsp. Legionella pneumophila subsp. Leptospira interrogans all serovars.

Leptospira interrogans spp. Listeria monocytogenes. Listeria ivanovii subsp. Listeria invanovii subsp. Morganella morganii subsp.

Mycobacterium abscessus subsp. Mycobacterium africanum. Mycobacterium avium subsp. Mycobacterium bovis. Mycobacterium caprae Mycobacterium tuberculosis subsp.

Mycobacterium chelonae. Mycobacterium chimaera. Mycobacterium fortuitum. Mycobacterium intracellulare. Mycobacterium kansasii.

Mycobacterium leprae. Mycobacterium malmoense. Mycobacterium marinum. Mycobacterium microti. Mycobacterium pinnipedii.

Mycobacterium scrofulaceum. Mycobacterium simiae. Mycobacterium szulgai. Mycobacterium tuberculosis.

Mycobacterium ulcerans. Mycobacterium xenopi. Mycoplasma hominis. Mycoplasma pneumoniae. Neisseria gonorrhoeae. Neisseria meningitidis. Neorickettsia sennetsu Rickettsia sennetsu, Ehrlichia sennetsu.

Nocardia asteroides. Nocardia brasiliensis. Nocardia farcinica. Nocardia otitidiscaviarum. Orientia tsutsugamushi Rickettsia tsutsugamushi. Pasteurella multocida subsp.

Pasteurella spp. Peptostreptococcus anaerobius. Plesiomonas shigelloides. Porphyromonas spp. Proteus mirabilis.

Proteus vulgaris. Providencia alcalifaciens Proteus inconstans. Providencia rettgeri Proteus rettgeri. Providencia spp.

Pseudomonas aeruginosa. Rhodococcus hoagii Corynebacterium equii. Rickettsia africae. Rickettsia akari. Rickettsia australis. Rickettsia canadensis. Rickettsia conorii.

Rickettsia heilongjiangensis. Rickettsia japonica. Rickettsia montanensis. Rickettsia typhi. Rickettsia prowazekii. Rickettsia rickettsii.

Rickettsia sibirica. Salmonella enterica choleraesuis subsp. Salmonella Enteritidis. Salmonella Paratyphi A, B, C. Salmonella Typhi. Salmonella Typhimurium.

Salmonella other serovars. Shigella dysenteriae Type 1. Shigella dysenteriae, other than Type 1. Shigella flexneri.

Staphylococcus aureus. Streptobacillus moniliformis. Streptococcus agalactiae. Streptococcus dysgalactiae subsp. Streptococcus pneumoniae. Streptococcus pyogenes.

Streptococcus suis. Streptococcus spp. Treponema carateum. Treponema pallidum. Treponema pertenue. Trueperella pyogenes.

Ureaplasma parvum. Ureaplasma urealyticum. Vibrio cholerae including El Tor. Vibrio parahaemolyticus Benecka parahaemolytica. Yersinia enterocolitica subsp.

Yersinia pseudotuberculosis. Hantaviridae F. Nairoviridae F. Peribunyaviridae F. Phenuiviridae F. Herpesviridae F. Paramyxoviridae F.

Pneumoviridae F. Rhabdoviridae F. Coronaviridae F. Picornaviridae F. Enterovirus D, Human Enterovirus type 70 Acute haemorrhagic conjunctivitis virus.

Adenoviridae F. Astroviridae F. Arenaviridae F. Caliciviridae F. Hepadnaviridae F. Flaviviridae F. Orthomyxoviridae F. Papillomaviridae F. Parvoviridae F.

Polyomaviridae F. Vaccinia virus incl. Retroviridae F. Acanthamoeba castellani. Ancylostoma duodenale. Angiostrongylus cantonensis.

Angiostrongylus costaricensis. Anisakis simplex. Ascaris lumbricoides. Babesia divergens. Balamuthia mandrillaris. Balantidium coli. Capillaria philippinensis.

Clonorchis sinensis Opisthorchis sinensis. Clonorchis viverrini Opisthirchis viverrini. Cryptosporidium hominis. Cryptosporidium parvum.

Cyclospora cayetanensis. Dicrocoelium dentriticum. Dipetalonema streptocerca. Diphyllobothrium latum. Dracunculus medinensis.

Echinococcus granulosus. Echinococcus multilocularis. Echinococcus oligarthrus. Echinococcus vogeli. Entamoeba histolytica.

Enterobius vermicularis. Enterocytozoon bieneusi. Fasciola gigantica. Fasciola hepatica. Fasciolopsis buski. Giardia lamblia Giardia duodenalis, Giardia intestinalis.

Heterophyes spp. Hymenolepis diminuta. Hymenolepis nana. Leishmania aethiopica. Leishmania braziliensis. Leishmania donovani. Leishmania guyanensis Viannia guyanensis.

Leishmania infantum Leishmania chagasi. Leishmania major. Leishmania mexicana. Leishmania panamensis Viannia panamensis. Leishmania peruviana.

Leishmania tropica. Mansonella ozzardi. Mansonella perstans. Mansonella streptocerca. Metagonimus spp. Naegleria fowleri.

Necator americanus. Onchocerca volvulus. Opisthorchis felineus. Opisthorchis spp. Paragonimus westermani. Paragonimus spp. Plasmodium falciparum.

Plasmodium knowlesi. Plasmodium spp. Sarcocystis suihominis. Schistosoma haematobium. Schistosoma intercalatum. Schistosoma japonicum. Schistosoma mansoni.

Schistosoma mekongi. Strongyloides stercoralis. Strongyloides spp. Toxoplasma gondii. Trichinella nativa.

Trichinella nelsoni. Trichinella pseudospiralis. Trichinella spiralis. Trichomonas vaginalis. Trichostrongylus orientalis.

Trichostrongylus spp. Trichuris trichiura. Trypanosoma brucei brucei. Trypanosoma brucei gambiense. Trypanosoma brucei rhodesiense.

Trypanosoma cruzi. Wuchereria bancrofti. Aspergillus flavus. Aspergillus fumigatus. Aspergillus spp.

Blastomyces dermatitidis Ajellomyces dermatitidis. Blastomyces gilchristii. Candida albicans. Candida dubliniensis.

Candida glabrata. Candida parapsilosis. Candida tropicalis. Cladophialophora bantiana Xylohypha bantiana, Cladosporium bantianum, trichoides.

Cladophialophora modesta. Cladophialophora spp. Coccidioides immitis. Coccidioides posadasii. Cryptococcus gattii Filobasidiella neoformans var.

Cryptococcus neoformans Filobasidiella neoformans var. Emmonsia parva var. Epidermophyton floccosum. Epidermophyton spp.

Fonsecaea pedrosoi. Histoplasma capsulatum. Histoplasma capsulatum var. Histoplasma duboisii. Madurella grisea. Madurella mycetomatis.

Microsporum spp. Neotestudina rosatii. Paracoccidioides brasiliensis. Paracoccidioides lutzii. Rhinocladiella mackenziei. Scedosporium apiospermum.

Scedosporium prolificans inflatum. Sporothrix schenckii. Talaromyces marneffei Penicillium marneffei.

Trichophyton rubrum. Trichophyton tonsurans. Trichophyton spp. Articles 15 3 and 16 1 a and b. The measures contained in this Annex shall be applied according to the nature of the activities, the assessment of risk to workers, and the nature of the biological agent concerned.

The workplace is to be separated from any other activities in the same building. Infected material including any animal is to be handled in a safety cabinet or isolation or other suitable containment.

An observation window, or, alternative, is to be present, so that occupants can be seen. Article 4 1 and Article 16 2 a.

For work with group 1 biological agents including live attenuated vaccines, the principles of good occupational safety and hygiene should be observed.

Groups 2, 3 and 4 biological agents. It may be appropriate to select and combine containment requirements from different categories below on the basis of a risk assessment related to any particular process or part of a process.

Viable organisms should be handled in a system which physically separates the process from the environment.

Sample collection, addition of materials to a closed system and transfer of viable organisms to another closed system, should be performed so as to:.

Bulk culture fluids should not be removed from the closed system unless the viable organisms have been:. The controlled area should be designed to contain spillage of the entire contents of the closed system.

The controlled area should be maintained at an air pressure negative to atmosphere. The controlled area should be adequately ventilated to minimise air contamination.

Effluent from sinks and showers should be collected and inactivated before release. Vaccination against hepatitis B virus will therefore protect workers who are not affected by hepatitis B virus against hepatitis delta virus.

As a precaution containment level 3 is recommended for work with them. The clean side of the airlock must be separated from the restricted side by changing or showering facilities and preferably by interlocking doors.

Skip to main content. This document is an excerpt from the EUR-Lex website. EU case-law Case-law Digital reports Directory of case-law. Quick search.

Search tips. Need more search options? Use the Advanced search. Help Print this page. Expand all Collapse all. Title and reference. Languages, formats and link to OJ.

Official Journal. To see if this document has been published in an e-OJ with legal value, click on the icon above For OJs published before 1st July , only the paper version has legal value.

Multilingual display. Article 2 1. Article 3 This Directive shall enter into force on the twentieth day following that of its publication in the Official Journal of the European Union.

Article 4 This Directive is addressed to the Member States. Done at Brussels, 24 October Work in food production plants.

Work in agriculture. Work in healthcare, including isolation and post-mortem units. Work in refuse disposal plants. Work in sewage purification installations.

In line with the scope of the Directive, only agents which are known to infect humans are to be included in the classified list.

Animal and plant pathogens which are known not to affect man are excluded. The list of classified agents is based on the effect of those agents on healthy workers.

Biological agents which have not been classified for inclusion in groups 2 to 4 of the list are not implicitly classified in group 1.

Where a strain is attenuated or has lost known virulence genes, then the containment required by the classification of its parent strain need not necessarily apply, subject to assessment appropriate for risk in the workplace.

The nomenclature of classified agents used to establish this list reflects and is in conformity with the latest international agreements of the taxonomy and nomenclature of agents at the time the list was prepared.

The list of classified biological agents reflects the state of knowledge at the time that it was devised. Member States are to ensure that all viruses which have already been isolated in humans and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.

The requirements as to containment consequent on the classification of parasites apply only to stages in the life cycle of the parasite in which it is liable to be infectious to humans at the workplace.

This list also gives a separate indication in cases where the biological agents are likely to cause allergic or toxic reactions, where an effective vaccine is available, or where it is advisable to keep a list of exposed workers for more than 10 years.

These indications are shown by the following letters: A: Possible allergic effects D: List of workers exposed to this biological agent to be kept for more than 10 years after the end of last known exposure T: Toxin production V: Effective vaccine available and registered within the EU The application of preventive vaccination should take account of the code of practice given in Annex VII.

Containment measures B. Containment levels 2 3 4 Workplace 1. The workplace is to be separated from any other activities in the same building No Recommended Yes 2.

The workplace is to be sealable to permit fumigation No Recommended Yes Facilities 3. Infected material including any animal is to be handled in a safety cabinet or isolation or other suitable containment Where appropriate Yes, where infection is by airborne route Yes Equipment 4.

The workplace is to be maintained at an air pressure negative to atmosphere No Recommended Yes 6. Surfaces impervious to water and easy to clean Yes, for bench and floor Yes, for bench, floor and other surfaces determined by risk assessment Yes, for bench, walls, floor and ceiling 7.

Surfaces resistant to acids, alkalis, solvents, disinfectants Recommended Yes Yes System of work 8.

Efficient vector control, for example rodents and insects Recommended Yes Yes Specified disinfection procedures Yes Yes Yes Safe storage of a biological agent Yes Yes Yes, secure storage Personnel should shower before leaving the contained area No Recommended Recommended Waste Validated inactivation process for the safe disposal of animal carcases Recommended Yes, on or off site Yes, on site Other measures A laboratory is to contain its own equipment No Recommended Yes An observation window, or, alternative, is to be present, so that occupants can be seen Recommended Recommended Yes.

Group 1 biological agents For work with group 1 biological agents including live attenuated vaccines, the principles of good occupational safety and hygiene should be observed.

Groups 2, 3 and 4 biological agents It may be appropriate to select and combine containment requirements from different categories below on the basis of a risk assessment related to any particular process or part of a process.

Containment levels 2 3 4 General 1. Viable organisms should be handled in a system which physically separates the process from the environment Yes Yes Yes 2.

Exhaust gases from the closed system should be treated so as to: Minimise release Prevent release Prevent release 3.

Sample collection, addition of materials to a closed system and transfer of viable organisms to another closed system, should be performed so as to: Minimise release Prevent release Prevent release 4.

Bulk culture fluids should not be removed from the closed system unless the viable organisms have been: Inactivated by validated chemical or physical means Inactivated by validated chemical or physical means Inactivated by validated chemical or physical means 5.

Seals should be designed so as to: Minimise release Prevent release Prevent release 6. The controlled area should be designed to contain spillage of the entire contents of the closed system No Recommended Yes 7.

The controlled area should be sealable to permit fumigation No Recommended Yes Facilities 8. Decontamination and washing facilities should be provided for personnel Yes Yes Yes Equipment 9.

The controlled area should be maintained at an air pressure negative to atmosphere No Recommended Yes The controlled area should be adequately ventilated to minimise air contamination Recommended Recommended Yes System of work Biohazard signs should be posted Recommended Yes Yes Personnel should shower before leaving the controlled area No Recommended Yes Personnel should wear protective clothing Yes, work clothing Yes Yes, complete change Waste Effluent from sinks and showers should be collected and inactivated before release No Recommended Yes Views Read Edit View history.

Help Learn to edit Community portal Recent changes Upload file. Download as PDF Printable version. Wikimedia Commons Wikiquote.

Archaeology — Architecture — Art Literature — Music. Rail transport — Science — Sports. Sovereign states — State leaders — Territorial governors — Religious leaders.

Births — Deaths. Establishments — Disestablishments. Balinese saka calendar. Bengali calendar. British Regnal year.

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Listeria invanovii subsp. Morganella morganii subsp. Mycobacterium abscessus subsp. Mycobacterium africanum. Mycobacterium avium subsp.

Mycobacterium bovis. Mycobacterium caprae Mycobacterium tuberculosis subsp. Mycobacterium chelonae. Mycobacterium chimaera.

Mycobacterium fortuitum. Mycobacterium intracellulare. Mycobacterium kansasii. Mycobacterium leprae. Mycobacterium malmoense.

Mycobacterium marinum. Mycobacterium microti. Mycobacterium pinnipedii. Mycobacterium scrofulaceum. Mycobacterium simiae. Mycobacterium szulgai.

Mycobacterium tuberculosis. Mycobacterium ulcerans. Mycobacterium xenopi. Mycoplasma hominis. Mycoplasma pneumoniae.

Neisseria gonorrhoeae. Neisseria meningitidis. Neorickettsia sennetsu Rickettsia sennetsu, Ehrlichia sennetsu. Nocardia asteroides.

Nocardia brasiliensis. Nocardia farcinica. Nocardia otitidiscaviarum. Orientia tsutsugamushi Rickettsia tsutsugamushi. Pasteurella multocida subsp.

Pasteurella spp. Peptostreptococcus anaerobius. Plesiomonas shigelloides. Porphyromonas spp. Proteus mirabilis. Proteus vulgaris. Providencia alcalifaciens Proteus inconstans.

Providencia rettgeri Proteus rettgeri. Providencia spp. Pseudomonas aeruginosa. Rhodococcus hoagii Corynebacterium equii.

Rickettsia africae. Rickettsia akari. Rickettsia australis. Rickettsia canadensis. Rickettsia conorii. Rickettsia heilongjiangensis. Rickettsia japonica.

Rickettsia montanensis. Rickettsia typhi. Rickettsia prowazekii. Rickettsia rickettsii. Rickettsia sibirica. Salmonella enterica choleraesuis subsp.

Salmonella Enteritidis. Salmonella Paratyphi A, B, C. Salmonella Typhi. Salmonella Typhimurium. Salmonella other serovars. Shigella dysenteriae Type 1.

Shigella dysenteriae, other than Type 1. Shigella flexneri. Staphylococcus aureus. Streptobacillus moniliformis.

Streptococcus agalactiae. Streptococcus dysgalactiae subsp. Streptococcus pneumoniae. Streptococcus pyogenes.

Streptococcus suis. Streptococcus spp. Treponema carateum. Treponema pallidum. Treponema pertenue. Trueperella pyogenes. Ureaplasma parvum. Ureaplasma urealyticum.

Vibrio cholerae including El Tor. Vibrio parahaemolyticus Benecka parahaemolytica. Yersinia enterocolitica subsp. Yersinia pseudotuberculosis.

Hantaviridae F. Nairoviridae F. Peribunyaviridae F. Phenuiviridae F. Herpesviridae F. Paramyxoviridae F.

Pneumoviridae F. Rhabdoviridae F. Coronaviridae F. Picornaviridae F. Enterovirus D, Human Enterovirus type 70 Acute haemorrhagic conjunctivitis virus.

Adenoviridae F. Astroviridae F. Arenaviridae F. Caliciviridae F. Hepadnaviridae F. Flaviviridae F. Orthomyxoviridae F.

Papillomaviridae F. Parvoviridae F. Polyomaviridae F. Vaccinia virus incl. Retroviridae F. Acanthamoeba castellani. Ancylostoma duodenale.

Angiostrongylus cantonensis. Angiostrongylus costaricensis. Anisakis simplex. Ascaris lumbricoides. Babesia divergens.

Balamuthia mandrillaris. Balantidium coli. Capillaria philippinensis. Clonorchis sinensis Opisthorchis sinensis. Clonorchis viverrini Opisthirchis viverrini.

Cryptosporidium hominis. Cryptosporidium parvum. Cyclospora cayetanensis. Dicrocoelium dentriticum. Dipetalonema streptocerca. Diphyllobothrium latum.

Dracunculus medinensis. Echinococcus granulosus. Echinococcus multilocularis. Echinococcus oligarthrus. Echinococcus vogeli. Entamoeba histolytica.

Enterobius vermicularis. Enterocytozoon bieneusi. Fasciola gigantica. Fasciola hepatica. Fasciolopsis buski. Giardia lamblia Giardia duodenalis, Giardia intestinalis.

Heterophyes spp. Hymenolepis diminuta. Hymenolepis nana. Leishmania aethiopica. Leishmania braziliensis. Leishmania donovani. Leishmania guyanensis Viannia guyanensis.

Leishmania infantum Leishmania chagasi. Leishmania major. Leishmania mexicana. Leishmania panamensis Viannia panamensis.

Leishmania peruviana. Leishmania tropica. Mansonella ozzardi. Mansonella perstans. Mansonella streptocerca. Metagonimus spp. Naegleria fowleri.

Necator americanus. Onchocerca volvulus. Opisthorchis felineus. Opisthorchis spp. Paragonimus westermani. Paragonimus spp. Plasmodium falciparum. Plasmodium knowlesi.

Plasmodium spp. Sarcocystis suihominis. Schistosoma haematobium. Schistosoma intercalatum. Schistosoma japonicum. Schistosoma mansoni.

Schistosoma mekongi. Strongyloides stercoralis. Strongyloides spp. Toxoplasma gondii. Trichinella nativa. Trichinella nelsoni. Trichinella pseudospiralis.

Trichinella spiralis. Trichomonas vaginalis. Trichostrongylus orientalis. Trichostrongylus spp. Trichuris trichiura. Trypanosoma brucei brucei.

Trypanosoma brucei gambiense. Trypanosoma brucei rhodesiense. Trypanosoma cruzi. Wuchereria bancrofti. Aspergillus flavus. Aspergillus fumigatus.

Aspergillus spp. Blastomyces dermatitidis Ajellomyces dermatitidis. Blastomyces gilchristii. Candida albicans. Candida dubliniensis. Candida glabrata.

Candida parapsilosis. Candida tropicalis. Cladophialophora bantiana Xylohypha bantiana, Cladosporium bantianum, trichoides. Cladophialophora modesta.

Cladophialophora spp. Coccidioides immitis. Coccidioides posadasii. Cryptococcus gattii Filobasidiella neoformans var. Cryptococcus neoformans Filobasidiella neoformans var.

Emmonsia parva var. Epidermophyton floccosum. Epidermophyton spp. Fonsecaea pedrosoi. Histoplasma capsulatum.

Histoplasma capsulatum var. Histoplasma duboisii. Madurella grisea. Madurella mycetomatis. Microsporum spp.

Neotestudina rosatii. Paracoccidioides brasiliensis. Paracoccidioides lutzii. Rhinocladiella mackenziei. Scedosporium apiospermum.

Scedosporium prolificans inflatum. Sporothrix schenckii. Talaromyces marneffei Penicillium marneffei. Trichophyton rubrum. Trichophyton tonsurans.

Trichophyton spp. Articles 15 3 and 16 1 a and b. The measures contained in this Annex shall be applied according to the nature of the activities, the assessment of risk to workers, and the nature of the biological agent concerned.

The workplace is to be separated from any other activities in the same building. Infected material including any animal is to be handled in a safety cabinet or isolation or other suitable containment.

An observation window, or, alternative, is to be present, so that occupants can be seen. Article 4 1 and Article 16 2 a. For work with group 1 biological agents including live attenuated vaccines, the principles of good occupational safety and hygiene should be observed.

Groups 2, 3 and 4 biological agents. It may be appropriate to select and combine containment requirements from different categories below on the basis of a risk assessment related to any particular process or part of a process.

Viable organisms should be handled in a system which physically separates the process from the environment. Sample collection, addition of materials to a closed system and transfer of viable organisms to another closed system, should be performed so as to:.

Bulk culture fluids should not be removed from the closed system unless the viable organisms have been:. The controlled area should be designed to contain spillage of the entire contents of the closed system.

The controlled area should be maintained at an air pressure negative to atmosphere. The controlled area should be adequately ventilated to minimise air contamination.

Effluent from sinks and showers should be collected and inactivated before release. Vaccination against hepatitis B virus will therefore protect workers who are not affected by hepatitis B virus against hepatitis delta virus.

As a precaution containment level 3 is recommended for work with them. The clean side of the airlock must be separated from the restricted side by changing or showering facilities and preferably by interlocking doors.

Skip to main content. This document is an excerpt from the EUR-Lex website. EU case-law Case-law Digital reports Directory of case-law.

Quick search. Search tips. Need more search options? Use the Advanced search. Help Print this page. Expand all Collapse all. Title and reference.

Languages, formats and link to OJ. Official Journal. To see if this document has been published in an e-OJ with legal value, click on the icon above For OJs published before 1st July , only the paper version has legal value.

Multilingual display. Article 2 1. Article 3 This Directive shall enter into force on the twentieth day following that of its publication in the Official Journal of the European Union.

Article 4 This Directive is addressed to the Member States. Done at Brussels, 24 October Work in food production plants. Work in agriculture.

Work in healthcare, including isolation and post-mortem units. Work in refuse disposal plants. Work in sewage purification installations.

In line with the scope of the Directive, only agents which are known to infect humans are to be included in the classified list. Animal and plant pathogens which are known not to affect man are excluded.

The list of classified agents is based on the effect of those agents on healthy workers. Biological agents which have not been classified for inclusion in groups 2 to 4 of the list are not implicitly classified in group 1.

Where a strain is attenuated or has lost known virulence genes, then the containment required by the classification of its parent strain need not necessarily apply, subject to assessment appropriate for risk in the workplace.

The nomenclature of classified agents used to establish this list reflects and is in conformity with the latest international agreements of the taxonomy and nomenclature of agents at the time the list was prepared.

The list of classified biological agents reflects the state of knowledge at the time that it was devised. Member States are to ensure that all viruses which have already been isolated in humans and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.

The requirements as to containment consequent on the classification of parasites apply only to stages in the life cycle of the parasite in which it is liable to be infectious to humans at the workplace.

This list also gives a separate indication in cases where the biological agents are likely to cause allergic or toxic reactions, where an effective vaccine is available, or where it is advisable to keep a list of exposed workers for more than 10 years.

These indications are shown by the following letters: A: Possible allergic effects D: List of workers exposed to this biological agent to be kept for more than 10 years after the end of last known exposure T: Toxin production V: Effective vaccine available and registered within the EU The application of preventive vaccination should take account of the code of practice given in Annex VII.

Containment measures B. Containment levels 2 3 4 Workplace 1. The workplace is to be separated from any other activities in the same building No Recommended Yes 2.

The workplace is to be sealable to permit fumigation No Recommended Yes Facilities 3. Infected material including any animal is to be handled in a safety cabinet or isolation or other suitable containment Where appropriate Yes, where infection is by airborne route Yes Equipment 4.

The workplace is to be maintained at an air pressure negative to atmosphere No Recommended Yes 6. Surfaces impervious to water and easy to clean Yes, for bench and floor Yes, for bench, floor and other surfaces determined by risk assessment Yes, for bench, walls, floor and ceiling 7.

Surfaces resistant to acids, alkalis, solvents, disinfectants Recommended Yes Yes System of work 8. Efficient vector control, for example rodents and insects Recommended Yes Yes Specified disinfection procedures Yes Yes Yes Safe storage of a biological agent Yes Yes Yes, secure storage Personnel should shower before leaving the contained area No Recommended Recommended Waste Validated inactivation process for the safe disposal of animal carcases Recommended Yes, on or off site Yes, on site Other measures A laboratory is to contain its own equipment No Recommended Yes An observation window, or, alternative, is to be present, so that occupants can be seen Recommended Recommended Yes.

Group 1 biological agents For work with group 1 biological agents including live attenuated vaccines, the principles of good occupational safety and hygiene should be observed.

Groups 2, 3 and 4 biological agents It may be appropriate to select and combine containment requirements from different categories below on the basis of a risk assessment related to any particular process or part of a process.

Containment levels 2 3 4 General 1. Viable organisms should be handled in a system which physically separates the process from the environment Yes Yes Yes 2.

Exhaust gases from the closed system should be treated so as to: Minimise release Prevent release Prevent release 3.

Sample collection, addition of materials to a closed system and transfer of viable organisms to another closed system, should be performed so as to: Minimise release Prevent release Prevent release 4.

Bulk culture fluids should not be removed from the closed system unless the viable organisms have been: Inactivated by validated chemical or physical means Inactivated by validated chemical or physical means Inactivated by validated chemical or physical means 5.

Seals should be designed so as to: Minimise release Prevent release Prevent release 6. The controlled area should be designed to contain spillage of the entire contents of the closed system No Recommended Yes 7.

The controlled area should be sealable to permit fumigation No Recommended Yes Facilities 8. Decontamination and washing facilities should be provided for personnel Yes Yes Yes Equipment 9.

The controlled area should be maintained at an air pressure negative to atmosphere No Recommended Yes The controlled area should be adequately ventilated to minimise air contamination Recommended Recommended Yes System of work Biohazard signs should be posted Recommended Yes Yes Personnel should shower before leaving the controlled area No Recommended Yes Personnel should wear protective clothing Yes, work clothing Yes Yes, complete change Waste Effluent from sinks and showers should be collected and inactivated before release No Recommended Yes Effluent treatment before final discharge Inactivated by validated chemical or physical means Inactivated by validated chemical or physical means Inactivated by validated chemical or physical means.

These indications are shown by the following letters: A:. Possible allergic effects. Toxin production. Effective vaccine available and registered within the EU.

Biological agent. Anaplasma spp. Bordetella spp. Borrelia spp. Brucella canis. Brucella suis. Ehrlichia spp. Klebsiella spp. Legionella spp.

Mycoplasma spp. Nocardia nova. Nocardia spp. Prevotella spp. Proteus penneri. Rickettsia spp. Shigella boydii.

Shigella sonnei. Treponema spp. Vibrio spp. Yersinia pestis. Yersinia spp. Biological agent virus species or indicated taxonomy order.

Bunyavirales O. Orthohantavirus G. Bayou orthohantavirus. Black Creek Canal orthohantavirus. Cano Delgadito orthohantavirus.

Choclo orthohantavirus. El Moro Canyon orthohantavirus. Laguna Negra orthohantavirus. Prospect Hill orthohantavirus.

Other hantaviruses known to be pathogenic. Orthonairovirus G. Crimean-Congo haemorrhagic fever orthonairovirus.

Dugbe orthonairovirus. Hazara orthonairovirus. Nairobi sheep disease orthonairovirus. Other nairoviruses known to be pathogenic. Orthobunyavirus G.

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